Počet záznamů: 1
Real/time monitoring of biomolecular interactions in blood plasma using a surface plasmon resonance biosensor
- 1.0350305 - ÚFE 2011 RIV DE eng J - Článek v odborném periodiku
Špringer, Tomáš - Piliarik, Marek - Homola, Jiří
Real/time monitoring of biomolecular interactions in blood plasma using a surface plasmon resonance biosensor.
Analytical and Bioanalytical Chemistry. Roč. 398, č. 5 (2010), s. 1955-1961. ISSN 1618-2642. E-ISSN 1618-2650
Grant CEP: GA AV ČR KAN200670701; GA MŠMT OC09058
Výzkumný záměr: CEZ:AV0Z20670512
Klíčová slova: surface plasmon resonance * molecular interaction analysis * microfluidics * optical biosensor
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 3.841, rok: 2010
We report a novel biosenor approach which enables real-time monitoring of biomolecular interactions in complex samples. This approach is demonstrated by investigating model interaction between the human chorionic gonadotropin and its antibody in blood plasma using a surface plasmon resonance biosensor and a novel dispersionless microfluidics. The proposed approach also significantly enhance capability of the biosensor to detect biomolecules in complex samples in terms of detection time and sensitivity.
Trvalý link: http://hdl.handle.net/11104/0190340
Počet záznamů: 1