Počet záznamů: 1
Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin
- 1.0334046 - ÚMG 2010 RIV US eng J - Článek v odborném periodiku
Katsetos, C.D. - Dráberová, Eduarda - Legido, A. - Dumontet, C. - Dráber, Pavel
Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin.
Journal of Cellular Physiology. Roč. 221, č. 3 (2009), s. 505-513. ISSN 0021-9541. E-ISSN 1097-4652
Grant CEP: GA AV ČR KAN200520701
Výzkumný záměr: CEZ:AV0Z50520514
Klíčová slova: Beta-II-tubulin * glioblastoma
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 4.586, rok: 2009
This minireview focuses on microtubules and tubulin as emerging targets in potential therapy of GBM using a new class of betaIII-tubulin-targeted drugs in the light of recent developments concerning the function and potential role of this isotype in clinically aggressive tumor behavior, cancer stem cells, tumor hypoxia and chemoresistance to tubulin binding agents, principally taxanes.
Trvalý link: http://hdl.handle.net/11104/0178881
Počet záznamů: 1