Počet záznamů: 1
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration
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SYSNO ASEP 0618502 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration Tvůrce(i) Zdouc, M. M. (NL)
Blin, K. (DK)
Louwen, N. L. L. (NL)
Navarro, J. (NL)
Loureiro, C. (NL)
Bader, C. D. (DE)
Bailey, C. B. (AU)
Barra, L. (DE)
Booth, T. J. (DK)
Bozhueyuek, K. A. J. (DE)
Cediel-Becerra, J. D. D. (US)
Charlop-Powers, Z. (US)
Chevrette, M. G. (US)
Chooi, Y. H. (AU)
D'Agostino, P. M. (DE)
de Rond, T. (NZ)
Del Pup, E. (NL)
Duncan, K. R. (GB)
Gu, W. (US)
Hanif, N. (ID)
Helfrich, E. J. N. (DE)
Jenner, M. (GB)
Katsuyama, Y. (JP)
Korenskaia, A. (DE)
Krug, D. (DE)
Damiani, Tito (UOCHB-X) ORCID
Hebra, Téo (UOCHB-X) ORCID
Sehnal, L. (CZ)
Weber, T. (DE)
Medema, M. H. (NL)Zdroj.dok. Nucleic Acids Research. - : Oxford University Press - ISSN 0305-1048
Roč. 53, č. 1 (2025), D678-D690Poč.str. 13 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké CEP EH22_010/0002733 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Způsob publikování Open access Institucionální podpora UOCHB-X - RVO:61388963 UT WOS 001443163100002 EID SCOPUS 85214414411 DOI https://doi.org/10.1093/nar/gkae1115 Anotace Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is governed by sets of co-regulated and physically clustered genes known as biosynthetic gene clusters (BGCs). To share information about BGCs in a standardized and machine-readable way, the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard and repository was initiated in 2015. Since its conception, MIBiG has been regularly updated to expand data coverage and remain up to date with innovations in natural product research. Here, we describe MIBiG version 4.0, an extensive update to the data repository and the underlying data standard. In a massive community annotation effort, 267 contributors performed 8304 edits, creating 557 new entries and modifying 590 existing entries, resulting in a new total of 3059 curated entries in MIBiG. Particular attention was paid to ensuring high data quality, with automated data validation using a newly developed custom submission portal prototype, paired with a novel peer-reviewing model. MIBiG 4.0 also takes steps towards a rolling release model and a broader involvement of the scientific community. MIBiG 4.0 is accessible online at https://mibig.secondarymetabolites.org/. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Rok sběru 2026 Elektronická adresa https://doi.org/10.1093/nar/gkae1115
Počet záznamů: 1