Počet záznamů: 1
Neurogenesis in Alzheimer´s disease
- 1.0367673 - ÚEM 2012 RIV GB eng J - Článek v odborném periodiku
Rodríguez Arellano, Jose Julio - Verkhratsky, Alexei
Neurogenesis in Alzheimer´s disease.
Journal of Anatomy. Roč. 219, č. 1 (2011), s. 78-89. ISSN 0021-8782. E-ISSN 1469-7580
Grant CEP: GA ČR GA309/09/1696; GA ČR(CZ) GAP304/11/0184; GA ČR GA309/08/1381; GA ČR GA305/08/1384
Výzkumný záměr: CEZ:AV0Z50390703
Klíčová slova: Alzheimer's disease * hippocampus * neurodegeneration
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 2.370, rok: 2011
Here, we overviewed the relations between adult neurogenesis and Alzheimer’s disease, and try to analyse the controversies in the field. We also summarised recent data obtained in the triple transgenic model of AD that show time- and region-specific impairment of neurogenesis, which may account for the early changes in synaptic plasticity and cognitive impairments that develop prior to gross neurodegenerative alterations and that could underlie new rescue therapies.
Trvalý link: http://hdl.handle.net/11104/0202265
Počet záznamů: 1