The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination reactions of purines

0360741 - ÚOCHB 2012 RIV GB eng J - Článek v odborném periodiku
Čechová, Lucie - Jansa, Petr - Šála, Michal - Dračínský, Martin - Holý, Antonín - Janeba, Zlatko
The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination reactions of purines.
Tetrahedron. Roč. 67, č. 5 (2011), s. 866-871. ISSN 0040-4020. E-ISSN 1464-5416
Grant CEP: GA MŠMT 1M0508; GA AV ČR KJB400550903
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: microwave-assisted synthesis * DMF * formamides * dehalogenative amination * purines
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 3.025, rok: 2011

The microwave-assisted decomposition of DMF was thoroughly studied and the reaction conditions (temperature, solvent effect, and effect of additives such as acids, bases, and salts) were optimized for its use in amination reactions. The applicability of this expedient methodology in purine chemistry and with various formamides is demonstrated.
Trvalý link: http://hdl.handle.net/11104/0198223