Počet záznamů: 1
Paramutation of tobacco transgenes by small RNA-mediated transcriptional gene silencing
- 1.0360303 - BFÚ 2012 RIV US eng J - Článek v odborném periodiku
Crhák Khaitová, Lucie - Fojtová, M. - Křížová, Kateřina - Lunerová Bedřichová, Jana - Fulneček, Jaroslav - Depicker, A. - Kovařík, Aleš
Paramutation of tobacco transgenes by small RNA-mediated transcriptional gene silencing.
Epigenetics. Roč. 6, č. 5 (2011), s. 650-660. ISSN 1559-2294. E-ISSN 1559-2308
Grant CEP: GA ČR(CZ) GD204/09/H002; GA MŠMT(CZ) LC06004
Grant ostatní: GA ČR(CZ) GPP501/11/P667
Program: GP
Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Klíčová slova: transcriptional gene silencing * transgene epialleles * DNA methylation
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 4.318, rok: 2011
In this work we show that the sensitivity of transgene loci to inherited silencing (paramutation) induced in trans by small RNA molecules depends on the structure and epigenetic state of target. The complex inverted repeat loci with methylation in the coding region are generally more sensitive than single copy insertions.
Trvalý link: http://hdl.handle.net/11104/0197884
Počet záznamů: 1