Počet záznamů: 1
Do we need new antibiotics? The search for new targets and new compounds
- 1.0351521 - MBÚ 2011 RIV DE eng J - Článek v odborném periodiku
Spížek, Jaroslav - Novotná, Jitka - Řezanka, Tomáš - Demain, L. A.
Do we need new antibiotics? The search for new targets and new compounds.
Journal of Industrial Microbiology & Biotechnology. Roč. 37, č. 12 (2010), s. 1241-1248. ISSN 1367-5435. E-ISSN 1476-5535
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: Antibiotics * Infectious diseases * Antibiotic resistance
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 2.416, rok: 2010
Resistance to antibiotics and other antimicrobial compounds continues to increase. There are several possibilities for protection against pathogenic microorganisms, for instance, preparation of new vaccines against resistant bacterial strains, use of specific bacteriophages, and searching for new antibiotics. The antibiotic search includes: (1) looking for new antibiotics from nontraditional or less traditional sources, (2) sequencing microbial genomes with the aim of finding genes specifying biosynthesis of antibiotics, (3) analyzing DNA from the environment (metagenomics), (4) reexamining forgotten natural compounds and products of their transformations, and (5) investigating new antibiotic targets in pathogenic bacteria
Trvalý link: http://hdl.handle.net/11104/0191257
Počet záznamů: 1