Počet záznamů: 1
Dependence of Multidrug Resistance Protein-Mediated Cyclic Nucleotide Efflux on the Background Sodium Conductance
- 1.0343224 - FGÚ 2011 RIV US eng J - Článek v odborném periodiku
Kučka, M. - Kretschmannová, K. - Murano, T. - Wu, Ch. P. - Zemková, Hana - Ambudkar, S. V. - Stojilkovic, S. S.
Dependence of Multidrug Resistance Protein-Mediated Cyclic Nucleotide Efflux on the Background Sodium Conductance.
Molecular Pharmacology. Roč. 77, č. 2 (2010), s. 270-279. ISSN 0026-895X. E-ISSN 1521-0111
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: multidrug resistance protein * cAMP * anterior pituitary
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 4.725, rok: 2010
Anterior pituitary cells fire action potentials and release cyclic nucleotides both spontaneously and in response to agonist stimulation. A tetrodotoxin-resistant background Na+ conductance is critical for firing of these action potentials. In these cells, multidrug resistance proteins MRP4 and MRP5 -mediated cyclic nucleotide efflux can be rapidly determined by the background Na+ conductance
Trvalý link: http://hdl.handle.net/11104/0185748
Počet záznamů: 1