Počet záznamů: 1
Shedding light on blue-green photosynthesis: A wavelength-dependent mathematical model of photosynthesis in iSynechocystis/i sp. PCC 6803
- 1.
SYSNO ASEP 0599397 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Shedding light on blue-green photosynthesis: A wavelength-dependent mathematical model of photosynthesis in iSynechocystis/i sp. PCC 6803 Tvůrce(i) Pfennig, T. (DE)
Kullmann, E. (DE)
Zavřel, Tomáš (UEK-B) RID, SAI, ORCID
Nakielski, A. (DE)
Ebenhoeh, O. (DE)
Červený, Jan (UEK-B) RID, ORCID, SAI
Bernát, G. (HU)
Matuszynska, A. B. (DE)Celkový počet autorů 8 Číslo článku e1012445 Zdroj.dok. PLoS Computational Biology - ISSN 1553-734X
Roč. 20, č. 9 (2024)Poč.str. 32 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova orange carotenoid protein ; electron-transport ; cyanobacteria ; quality ; energy ; transitions ; pathways ; pcc-6803 ; co2 Vědní obor RIV EA - Morfologické obory a cytologie Obor OECD Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology CEP LM2018123 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy EF16_026/0008413 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy LUAUS24149 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Způsob publikování Open access Institucionální podpora UEK-B - RVO:86652079 UT WOS 001312594500002 EID SCOPUS 85204073705 DOI https://doi.org/10.1371/journal.pcbi.1012445 Anotace Cyanobacteria hold great potential to revolutionize conventional industries and farming practices with their light-driven chemical production. To fully exploit their photosynthetic capacity and enhance product yield, it is crucial to investigate their intricate interplay with the environment including the light intensity and spectrum. Mathematical models provide valuable insights for optimizing strategies in this pursuit. In this study, we present an ordinary differential equation-based model for the cyanobacterium Synechocystis sp. PCC 6803 to assess its performance under various light sources, including monochromatic light. Our model can reproduce a variety of physiologically measured quantities, e.g. experimentally reported partitioning of electrons through four main pathways, O-2 evolution, and the rate of carbon fixation for ambient and saturated CO2. By capturing the interactions between different components of a photosynthetic system, our model helps in understanding the underlying mechanisms driving system behavior. Our model qualitatively reproduces fluorescence emitted under various light regimes, replicating Pulse-amplitude modulation (PAM) fluorometry experiments with saturating pulses. Using our model, we test four hypothesized mechanisms of cyanobacterial state transitions for ensemble of parameter sets and found no physiological benefit of a model assuming phycobilisome detachment. Moreover, we evaluate metabolic control for biotechnological production under diverse light colors and irradiances. We suggest gene targets for overexpression under different illuminations to increase the yield. By offering a comprehensive computational model of cyanobacterial photosynthesis, our work enhances the basic understanding of light-dependent cyanobacterial behavior and sets the first wavelength-dependent framework to systematically test their producing capacity for biocatalysis. Pracoviště Ústav výzkumu globální změny Kontakt Nikola Šviková, svikova.n@czechglobe.cz, Tel.: 511 192 268 Rok sběru 2025 Elektronická adresa https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012445
Počet záznamů: 1