Počet záznamů: 1
Uncovering the Interrelation between Metabolite Profiles and Bioactivity of In Vitro- and Wild-Grown Catmint (Nepeta nuda L.)
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SYSNO ASEP 0578584 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Uncovering the Interrelation between Metabolite Profiles and Bioactivity of In Vitro- and Wild-Grown Catmint (Nepeta nuda L.) Tvůrce(i) Zaharieva, A. (BG)
Rusanov, K. (BG)
Rusanova, M. (BG)
Paunov, M. (BG)
Yordanova, Z. (BG)
Mantovska, D. (BG)
Tsacheva, I. (BG)
Petrova, D. (BG)
Mishev, K. (BG)
Dobrev, Petre (UEB-Q) RID, ORCID
Lacek, Jozef (UEB-Q) ORCID
Filepová, Roberta (UEB-Q) SAI, RID
Zehirov, G. (BG)
Vassileva, V. (BG)
Mišić, D. (RS)
Motyka, Václav (UEB-Q) RID, ORCID
Chaneva, G. (BG)
Zhiponova, M. (BG)Celkový počet autorů 18 Číslo článku 1099 Zdroj.dok. Metabolites. - : MDPI - ISSN 2218-1989
Roč. 13, č. 10 (2023)Poč.str. 18 s. Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova bioactivity ; gc-ms ; metabolites ; Nepeta nuda ; phytohormones ; volatiles Obor OECD Biochemical research methods Způsob publikování Open access Institucionální podpora UEB-Q - RVO:61389030 UT WOS 001098044200001 EID SCOPUS 85175351451 DOI https://doi.org/10.3390/metabo13101099 Anotace Nepeta nuda L. is a medicinal plant enriched with secondary metabolites serving to attract pollinators and deter herbivores. Phenolics and iridoids of N. nuda have been extensively investigated because of their beneficial impacts on human health. This study explores the chemical profiles of in vitro shoots and wild-grown N. nuda plants (flowers and leaves) through metabolomic analysis utilizing gas chromatography and mass spectrometry (GC–MS). Initially, we examined the differences in the volatiles’ composition in in vitro-cultivated shoots comparing them with flowers and leaves from plants growing in natural environment. The characteristic iridoid 4a-α,7-β,7a-α-nepetalactone was highly represented in shoots of in vitro plants and in flowers of plants from nature populations, whereas most of the monoterpenes were abundant in leaves of wild-grown plants. The known in vitro biological activities encompassing antioxidant, antiviral, antibacterial potentials alongside the newly assessed anti-inflammatory effects exhibited consistent associations with the total content of phenolics, reducing sugars, and the identified metabolic profiles in polar (organic acids, amino acids, alcohols, sugars, phenolics) and non-polar (fatty acids, alkanes, sterols) fractions. Phytohormonal levels were also quantified to infer the regulatory pathways governing phytochemical production. The overall dataset highlighted compounds with the potential to contribute to N. nuda bioactivity. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2024 Elektronická adresa https://doi.org/10.3390/metabo13101099
Počet záznamů: 1