Počet záznamů: 1
De novo emergence, existence, and demise of a protein-coding gene in murids
- 1.0567476 - ÚMG 2023 RIV GB eng J - Článek v odborném periodiku
Petržílek, Jan - Pasulka, Josef - Malík, Radek - Horvat, Filip - Kataruka, Shubhangini - Fulka, Helena - Svoboda, Petr
De novo emergence, existence, and demise of a protein-coding gene in murids.
BMC BIOLOGY. Roč. 20, č. 1 (2022), č. článku 272. E-ISSN 1741-7007
Grant CEP: GA MŠMT(CZ) EF18_046/0016045; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) LM2018126
GRANT EU: European Commission(XE) 647403 - D-FENS
Výzkumná infrastruktura: e-INFRA CZ - 90140
Institucionální podpora: RVO:68378050
Klíčová slova: De novo * Gene * Evolution * ltr * Retrotransposon * cag * Polyserine * D6Ertd527e * Oocyte
Obor OECD: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Impakt faktor: 5.4, rok: 2022
Způsob publikování: Open access
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01470-5
Background: Genes, principal units of genetic information, vary in complexity and evolutionary history. Less-complex genes (e.g., long non-coding RNA (lncRNA) expressing genes) readily emerge de novo from non-genic sequences and have high evolutionary turnover. Genesis of a gene may be facilitated by adoption of functional genic sequences from retrotransposon insertions. However, protein-coding sequences in extant genomes rarely lack any connection to an ancestral protein-coding sequence.
Trvalý link: https://hdl.handle.net/11104/0338724
Počet záznamů: 1