Počet záznamů: 1
Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth
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SYSNO ASEP 0553039 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth Tvůrce(i) Nordahl, E.R. (US)
Uthamaraj, S. (US)
Dennis, K.D. (US)
Sejkorová, A. (CZ)
Hejčl, Aleš (UEM-P) RID, ORCID
Hron, J. (CZ)
Svihlová, H. (CZ)
Carlson, K.D. (US)
Suzen, Y.B. (US)
Dragomir-Daescu, D. (US)Číslo článku 520 Zdroj.dok. Brain Sciences. - : MDPI
Roč. 11, č. 4 (2021)Poč.str. 10 s. Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova hemodynamics ; aneurysm growth ; computational fluid dynamics ; oscillatory shear index ; wall shear stress ; kinetic energy Vědní obor RIV FH - Neurologie, neurochirurgie, neurovědy Obor OECD Neurosciences (including psychophysiology Způsob publikování Open access Institucionální podpora UEM-P - RVO:68378041 UT WOS 000642782300001 EID SCOPUS 85105002936 DOI 10.3390/brainsci11040520 Anotace Computational fluid dynamics (CFD) has grown as a tool to help understand the hemodynamic properties related to the rupture of cerebral aneurysms. Few of these studies deal specifically with aneurysm growth and most only use a single time instance within the aneurysm growth history. The present retrospective study investigated four patient-specific aneurysms, once at initial diagnosis and then at follow-up, to analyze hemodynamic and morphological changes. Aneurysm geometries were segmented via the medical image processing software Mimics. The geometries were meshed and a computational fluid dynamics (CFD) analysis was performed using ANSYS. Results showed that major geometry bulk growth occurred in areas of low wall shear stress (WSS). Wall shape remodeling near neck impingement regions occurred in areas with large gradients of WSS and oscillatory shear index. This study found that growth occurred in areas where low WSS was accompanied by high velocity gradients between the aneurysm wall and large swirling flow structures. A new finding was that all cases showed an increase in kinetic energy from the first time point to the second, and this change in kinetic energy seems correlated to the change in aneurysm volume. Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2022 Elektronická adresa https://www.mdpi.com/2076-3425/11/4/520
Počet záznamů: 1