Počet záznamů: 1
Cationic polymer-coated magnetic nanoparticles with antibacterial properties: synthesis and in vitro characterization
- 1.0545226 - ÚMCH 2022 RIV CH eng J - Článek v odborném periodiku
Shatan, Anastasiia-Bohdana - Patsula, Vitalii - Dydowiczová, Aneta - Gunár, Kristýna - Velychkivska, Nadiia - Hromádková, Jiřina - Petrovský, Eduard - Horák, Daniel
Cationic polymer-coated magnetic nanoparticles with antibacterial properties: synthesis and in vitro characterization.
Antibiotics (Basel). Roč. 10, č. 9 (2021), č. článku 1077. ISSN 2079-6382. E-ISSN 2079-6382
Grant CEP: GA ČR(CZ) GC20-02177J
Institucionální podpora: RVO:61389013 ; RVO:67985530
Klíčová slova: magnetic * nanoparticles * antibacterial activity
Obor OECD: Polymer science; Physical geography (GFU-E)
Impakt faktor: 5.222, rok: 2021
Způsob publikování: Open access
https://www.mdpi.com/2079-6382/10/9/1077
Uniformly sized magnetite nanoparticles (Dn = 16 nm) were prepared by a thermal decomposition of Fe(III) oleate in octadec-1-ene and stabilized by oleic acid. The particles were coated with Sipomer PAM-200 containing both phosphate and methacrylic groups available for the attachment to the iron oxide and at the same time enabling (co)polymerization of 2-(dimethylamino)ethyl methacrylate and/or 2-tert-butylaminoethyl methacrylate at two molar ratios. The poly[2-(dimethylamino)ethyl methacrylate] (PDMAEMA) and poly[2-(dimethylamino)ethyl methacrylate-co-2-tert-butylaminoethyl methacrylate] [P(DMAEMA-TBAEMA)] polymers and the particles were characterized by 1H NMR spectroscopy, size-exclusion chromatography, transmission electron microscopy, dynamic light scattering, thermogravimetric analysis, magnetometry, and ATR FTIR and atomic absorption spectroscopy. The antimicrobial effect of cationic polymer-coated magnetite nanoparticles tested on both Escherichia coli and Staphylococcus aureus bacteria was found to be time- and dose-responsive. The P(DMAEMA-TBAEMA)-coated magnetite particles possessed superior biocidal properties compared to those of P(DMAEMA)-coated one.
Trvalý link: http://hdl.handle.net/11104/0322337
Počet záznamů: 1