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Current and Future Aspects of Nanomedicine
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SYSNO ASEP 0534382 Druh ASEP M - Kapitola v monografii Zařazení RIV C - Kapitola v knize Název Nanofibrous Scaffolds for Skin Tissue Engineering and Wound Healing Based on Nature-Derived Polymers Tvůrce(i) Bačáková, Lucie (FGU-C) RID, ORCID
Pajorová, Julia (FGU-C)
Zikmundová, Markéta (FGU-C)
Filová, Elena (FGU-C) RID, ORCID
Mikeš, P. (CZ)
Jenčová, V. (CZ)
Kuželová Košťáková, E. (CZ)
Sinica, A. (CZ)Zdroj.dok. Current and Future Aspects of Nanomedicine. - London : IntechOpen, 2020 / Khalil Islam - ISBN 978-1-78985-870-9 Rozsah stran s. 1-30 Poč.str. 30 s. Poč.str.knihy 142 Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova skin replacements ; wound dressings ; nanofibers ; electrospinning ; dermis ; epidermis ; keratinocytes ; fibroblasts ; stem cells ; vascularization ; cell delivery ; drug delivery ; regenerative medicine Vědní obor RIV EI - Biotechnologie a bionika Obor OECD Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction) CEP GA17-02448S GA ČR - Grantová agentura ČR GA17-00885S GA ČR - Grantová agentura ČR Institucionální podpora FGU-C - RVO:67985823 DOI https://doi.org/10.5772/intechopen.88602 Anotace Nanofibrous scaffolds belong to the most suitable materials for tissue engineering, because they mimic the fibrous component of the natural extracellular matrix. This chapter is focused on the application of nanofibers in skin tissue engineering and wound healing, because the skin is the largest and vitally important organ in the human body. Nanofibrous meshes can serve as substrates for adhesion, growth and differentiation of skin and stem cells, and also as an antimicrobial and moisture-retaining barrier. These meshes have been prepared from a wide range of synthetic and nature-derived polymers. This chapter is focused on the use of nature-derived polymers. These polymers have good or limited degradability in the human tissues, which depends on their origin and on the presence of appropriate enzymes in the human tissues. Non-degradable and less-degradable polymers are usually produced in bacteria, fungi, algae, plants or insects, and include, for example, cellulose, dextran, pullulan, alginate, pectin and silk fibroin. Well-degradable polymers are usually components of the extracellular matrix in the human body or at least in other vertebrates, and include collagen, elastin, keratin and hyaluronic acid, although some polymers produced by non-vertebrate organisms, such as chitosan or poly(3-hydroxybutyrate-co-3-hydroxyvalerate), are also degradable in the human body. Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2021 Elektronická adresa https://www.intechopen.com/online-first/nanofibrous-scaffolds-for-skin-tissue-engineering-and-wound-healing-based-on-nature-derived-polymers
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