Počet záznamů: 1
Long-term Cognitive Trajectory and Activities of Daily Living in Healthy Aging
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SYSNO ASEP 0523887 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Long-term Cognitive Trajectory and Activities of Daily Living in Healthy Aging Tvůrce(i) Bezdíček, O. (CZ)
Červenková, M. (CZ)
Georgi, H. (CZ)
Schmand, B. (CZ)
Hladká, Adéla (UIVT-O) SAI, ORCID, RID
Rulseh, A. (CZ)
Kopeček, M. (CZ)Zdroj.dok. Clinical Neuropsychologist. - : Taylor & Francis - ISSN 1385-4046
Roč. 35, č. 8 (2021), s. 1381-1397Poč.str. 17 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova Activities of daily living ; ageing ; brain maintenance ; longitudinal study ; MRI ; successful memory ageing Vědní obor RIV AN - Psychologie Obor OECD Neurosciences (including psychophysiology Způsob publikování Omezený přístup Institucionální podpora UIVT-O - RVO:67985807 UT WOS 000527258000001 EID SCOPUS 85083634600 DOI 10.1080/13854046.2020.1745895 Anotace OBJECTIVE: The purpose of the present study was to investigate if participants in NANOK study (National Normative Study of Cognitive Determinants of Healthy Ageing) who show no cognitive decline throughout five years (successful healthy agers, SHA) will show less age-related differences in instrumental activities of daily living (IADL) based on Functional Activities Questionnaire in comparison to participants who show subtle cognitive decline (Decliners) over time. METHOD: We used two different classifications of SHA: Rogalski (N = 25 SHA and N = 15 Decliners) based on cross-sectional neuropsychology measures and linear mixed model (LMEM, 20 SHA and 20 Decliners) based on the Montreal Cognitive Assessment longitudinal 5-years follow-up. Whole-brain T1- and T2-weighted images were corrected for distortions and segmented using Freesurfer. Whole-brain volumetry was performed using FSL’s voxel-based morphometry tool. RESULTS: The cognitive decline after four years follow-up but not age predicts subtle impairment in IADL in healthy ageing participants. We found brain volumetric differences between SHA and Decliners based on Rogalski but not LMEM classification especially in bilateral insular cortices and ventrolateral frontal cortex. The logistic regression model achieved an accuracy of 75% for the Rogalski in comparison to 67.5% for the LMEM classification. CONCLUSIONS: Slight restrictions in IADL seem to be a useful tool for screening healthy ageing participants at risk of developing subtle cognitive decline over a period of five years and the cross-sectional Rogalski criteria based on standardized neuropsychological measures were superior for tapping age-related brain changes to longitudinal LMEM classification based on screening (Montreal Cognitive Assessment). Pracoviště Ústav informatiky Kontakt Tereza Šírová, sirova@cs.cas.cz, Tel.: 266 053 800 Rok sběru 2022 Elektronická adresa http://dx.doi.org/10.1080/13854046.2020.1745895
Počet záznamů: 1