A Novel Method for Synthesis of cis-Zeatin and Its Valuable Precursor (Z)-4-Chloro-2-methyl-but-2-en-1-ol

0507491 - ÚEB 2020 RIV US eng J - Článek v odborném periodiku
Hanuš, Jan - Nisler, Jaroslav - Strnad, Miroslav
A Novel Method for Synthesis of cis-Zeatin and Its Valuable Precursor (Z)-4-Chloro-2-methyl-but-2-en-1-ol.
Organic Preparations and Procedures International. Roč. 51, č. 4 (2019), s. 368-374. ISSN 0030-4948. E-ISSN 1945-5453
Grant CEP: GA MŠMT(CZ) LO1204; GA ČR GA15-22322S
Institucionální podpora: RVO:61389030
Klíčová slova: Zeatin * ISOPRENOIDS * PATHWAY
Obor OECD: Organic chemistry
Impakt faktor: 0.847, rok: 2019
Způsob publikování: Open access
http://doi.org/10.1080/00304948.2019.1609817

Cytokinins are one of the major groups of plant hormones. The vast majority of naturally
occurring cytokinins are derivatives of zeatin and isopentenyladenine. Zeatin, 2-
methyl-4-(7H-purin-6-ylamino)but-2-en-1-ol, occurs as two stereoisomers, E and Z,
referring to the position of the terminal hydroxyl group on the isoprenoid side chain.
Both isomers play key roles in plant development and occur ubiquitously in the plant
kingdom. However, whereas the chemistry of (E)-zeatin is well-developed and the
compound is synthetically available by several methods, the synthesis of pure (Z)-
zeatin is problematic and in all cases generates low yield.
Trvalý link: http://hdl.handle.net/11104/0298471