Počet záznamů: 1
Genomic imprinting mediates dosage compensation in a young plant XY system
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SYSNO ASEP 0495629 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Genomic imprinting mediates dosage compensation in a young plant XY system Tvůrce(i) Muyle, A. (FR)
Zemp, N. (CH)
Fruchard, C. (FR)
Čegan, R. (CZ)
Vrána, Jan (UEB-Q) RID, ORCID
Deschamps, C. (FR)
Tavares, R. (FR)
Hobza, Roman (UEB-Q) RID, ORCID
Picard, F. (CZ)
Widmer, A. (CH)
Marais, G.A.B. (FR)Celkový počet autorů 11 Zdroj.dok. Nature Plants - ISSN 2055-026X
Roč. 4, č. 9 (2018), s. 677-680Poč.str. 4 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova y-chromosome degeneration ; biased gene-expression ; sex-chromosomes ; evolution ; inactivation ; patterns ; mammals ; facts ; model Vědní obor RIV EF - Botanika Obor OECD Plant sciences, botany CEP GA16-08698S GA ČR - Grantová agentura ČR Institucionální podpora UEB-Q - RVO:61389030 UT WOS 000446639100018 EID SCOPUS 85052331627 DOI 10.1038/s41477-018-0221-y Anotace Sex chromosomes have repeatedly evolved from a pair of autosomes. Consequently, X and Y chromosomes initially have similar gene content, but ongoing Y degeneration leads to reduced expression and eventual loss of Y genes(1). The resulting imbalance in gene expression between Y genes and the rest of the genome is expected to reduce male fitness, especially when protein networks have components from both autosomes and sex chromosomes. A diverse set of dosage compensating mechanisms that alleviates these negative effects has been described in animals(2-4). However, the early steps in the evolution of dosage compensation remain unknown, and dosage compensation is poorly understood in plants(5). Here, we describe a dosage compensation mechanism in the evolutionarily young XY sex determination system of the plant Silene latifolia. Genomic imprinting results in higher expression from the maternal X chromosome in both males and females. This compensates for reduced Y expression in males, but results in X overexpression in females and may be detrimental. It could represent a transient early stage in the evolution of dosage compensation. Our finding has striking resemblance to the first stage proposed by Ohno(6) for the evolution of X inactivation in mammals. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2019
Počet záznamů: 1