Počet záznamů: 1
Remnants of an Ancient Deltaretrovirus in the Genomes of Horseshoe Bats (Rhinolophidae)
- 1.0494059 - ÚMG 2019 RIV CH eng J - Článek v odborném periodiku
Hron, Tomáš - Farkašová, Helena - Gifford, R.J. - Benda, P. - Hulva, P. - Gorfol, T. - Pačes, Jan - Elleder, Daniel
Remnants of an Ancient Deltaretrovirus in the Genomes of Horseshoe Bats (Rhinolophidae).
Viruses. Roč. 10, č. 4 (2018), č. článku 185. E-ISSN 1999-4915
Grant CEP: GA MŠMT(CZ) LK11215; GA MŠMT(CZ) LM2015047
Institucionální podpora: RVO:68378050
Klíčová slova: endogenous retroviruses * retrovirus * evolution * Deltaretrovirus * genomics * bats
Obor OECD: Virology
Impakt faktor: 3.811, rok: 2018
Endogenous retrovirus (ERV) sequences provide a rich source of information about the long-term interactions between retroviruses and their hosts. However, most ERVs are derived from a subset of retrovirus groups, while ERVs derived from certain other groups remain extremely rare. In particular, only a single ERV sequence has been identified that shows evidence of being related to an ancient Deltaretrovirus, despite the large number of vertebrate genome sequences now available. In this report, we identify a second example of an ERV sequence putatively derived from a past deltaretroviral infection, in the genomes of several species of horseshoe bats (Rhinolophidae). This sequence represents a fragment of viral genome derived from a single integration. The time of the integration was estimated to be 11-19 million years ago. This finding, together with the previously identified endogenous Deltaretrovirus in long-fingered bats (Miniopteridae), suggest a close association of bats with ancient deltaretroviruses.
Trvalý link: http://hdl.handle.net/11104/0287292
Počet záznamů: 1