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Five-Year Neuropsychological Outcome after Stereotactic Radiofrequency Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy: Longitudinal Study
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SYSNO ASEP 0478411 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Five-Year Neuropsychological Outcome after Stereotactic Radiofrequency Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy: Longitudinal Study Tvůrce(i) Krámská, L. (CZ)
Vojtěch, Z. (CZ)
Lukavský, Jiří (PSU-E) RID, ORCID, SAI
Stará, M. (CZ)
Malíková, H. (CZ)Zdroj.dok. Stereotactic and Functional Neurosurgery - ISSN 1011-6125
Roč. 95, č. 3 (2017), s. 149-157Poč.str. 9 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova Cognitive outcome ; Memory ; Temporal lobe epilepsy ; Stereotactic surgery Vědní obor RIV FH - Neurologie, neurochirurgie, neurovědy Obor OECD Psychology (including human - machine relations) Institucionální podpora PSU-E - RVO:68081740 UT WOS 000405110200003 EID SCOPUS 85019853197 DOI 10.1159/000468527 Anotace Purpose: To assess the neuropsychological performance recoded over a period of 5 years after stereotactic radiofrequency amygdalohippocampectomy (SAHE) in the treatment of mesial temporal lobe epilepsy. Material and Methods: Thirty patients (mean age 38 years, 14 females/16 males) were included in this study. Twenty-one patients were treated on the left side, 9 on the right. Patients underwent neuropsychological evaluation by the Wechsler Adult Intelligence Scale-Revised and the Wechsler Memory Scale-Revised preoperatively and 5 years after SAHE. Results: Twenty-three (77%) patients were classified as Engel class I. At the group level, we found significant increases in all intelligence domains (Global, Visual, and Performance) by 19.1 (7.4), 15.8 (6.1), and 19.1 (7.9) points, respectively. Significant improvements were also detected in all memory measures (Global, Verbal, Visual, Attention/Concentration, Delayed Recall) by 19.4 (14.2), 16.9 (13.3), 19.0 (14.7), 15.3 (15.0), and 24.6 (13.4), respectively. Patients with left-sided surgery improved significantly more in Attention/Concentration. Otherwise, there were no statistically significant differences in memory function improvements between subgroups according to the operated side. Conclusion: After SAHE, we found favorable long-term neuropsychological outcomes. These results could be caused by incomplete destruction of target structures and minimization of collateral damage that possibly enables adaptive postoperative neuronal reorganization. Pracoviště Psychologický ústav Kontakt Štěpánka Halamová, Halamova@praha.psu.cas.cz, Tel.: 222 222 096 Rok sběru 2018
Počet záznamů: 1