Block and gradient copoly(2-oxazoline) micelles: strikingly different on the inside

Filippov, Sergey K.; Verbraeken, B.; Konarev, P. V.; Svergun, D. I.; Angelov, Borislav; Vishnevetskaya, N. S.; Papadakis, C. M.; Rogers, S.; Radulescu, A.; Courtin, T.; Martins, J. C.; Starovoytova, Larisa; Hrubý, Martin; Štěpánek, Petr; Kravchenko, V. S.; Potemkin, I. I.; Hoogenboom, R.

doi:https://dx.doi.org/10.1021/acs.jpclett.7b01588

Počet záznamů: 1

Block and gradient copoly(2-oxazoline) micelles: strikingly different on the inside

1.

SYSNO ASEP	0476710
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Block and gradient copoly(2-oxazoline) micelles: strikingly different on the inside
Tvůrce(i)	Filippov, Sergey K. (UMCH-V)_{RID, ORCID, SAI} Verbraeken, B. (BE) Konarev, P. V. (DE) Svergun, D. I. (DE) Angelov, Borislav (FZU-D)_ORCID Vishnevetskaya, N. S. (DE) Papadakis, C. M. (DE) Rogers, S. (GB) Radulescu, A. (DE) Courtin, T. (BE) Martins, J. C. (BE) Starovoytova, Larisa (UMCH-V)_RID Hrubý, Martin (UMCH-V)_{RID, ORCID} Štěpánek, Petr (UMCH-V)_{RID, ORCID} Kravchenko, V. S. (RU) Potemkin, I. I. (RU) Hoogenboom, R. (BE)
Zdroj.dok.	Journal of Physical Chemistry Letters. - : American Chemical Society - ISSN 1948-7185 Roč. 8, č. 16 (2017), s. 3800-3804
Poč.str.	5 s.
Jazyk dok.	eng - angličtina
Země vyd.	US - Spojené státy americké
Klíč. slova	poly(2-oxazolines) ; micelles ; gradient
Vědní obor RIV	BO - Biofyzika
Obor OECD	Biophysics
Vědní obor RIV – spolupráce	Fyzikální ústav - Biofyzika
CEP	GA17-00973S GA ČR - Grantová agentura ČR
	GA16-03156S GA ČR - Grantová agentura ČR
	NV15-25781A GA MZd - Ministerstvo zdravotnictví
Institucionální podpora	UMCH-V - RVO:61389013 ; FZU-D - RVO:68378271
UT WOS	000408187400014
EID SCOPUS	85027447566
DOI	10.1021/acs.jpclett.7b01588
Anotace	Herein, we provide a direct proof for differences in the micellar structure of amphiphilic diblock and gradient copolymers, thereby unambiguously demonstrating the influence of monomer distribution along the polymer chains on the micellization behavior. The internal structure of amphiphilic block and gradient co poly(2-oxazolines) based on the hydrophilic poly(2-methyl-2-oxazoline) (PMeOx) and the hydrophobic poly(2-phenyl-2-oxazoline) (PPhOx) was studied in water and water–ethanol mixtures by small-angle X-ray scattering (SAXS), small-angle neutron scattering (SANS), static and dynamic light scattering (SLS/DLS), and 1H NMR spectroscopy. Contrast matching SANS experiments revealed that block copolymers form micelles with a uniform density profile of the core. In contrast to popular assumption, the outer part of the core of the gradient copolymer micelles has a distinctly higher density than the middle of the core. We attribute the latter finding to back-folding of chains resulting from hydrophilic–hydrophobic interactions, leading to a new type of micelles that we refer to as micelles with a “bitterball-core” structure.
Pracoviště	Ústav makromolekulární chemie
Kontakt	Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
Rok sběru	2018

Počet záznamů: 1