Počet záznamů: 1
Non-steroidal anti-inflammatory drugs in the watercourses of Elbe basin in Czech Republic
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SYSNO ASEP 0475711 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Non-steroidal anti-inflammatory drugs in the watercourses of Elbe basin in Czech Republic Tvůrce(i) Maršík, Petr (UEB-Q) RID, ORCID
Rezek, Jan (UEB-Q) RID, ORCID
Židková, Monika (UEB-Q)
Kramulová, Barbora (UEB-Q)
Tauchen, J. (CZ)
Vaněk, Tomáš (UEB-Q) RID, ORCIDCelkový počet autorů 6 Zdroj.dok. Chemosphere. - : Elsevier - ISSN 0045-6535
Roč. 171, MAR (2017), s. 97-105Poč.str. 9 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova chromatography-mass-spectrometry ; gas-chromatography ; human pharmaceuticals ; waste-water ; surface-water ; risk-assessment ; diclofenac ; ibuprofen ; products ; plants ; NSAID Surface water ; Pharmaceuticals ; GCxGC-TOFMS Elbe basin ; Czech Republic Vědní obor RIV CE - Biochemie Obor OECD Environmental biotechnology CEP GA14-22593S GA ČR - Grantová agentura ČR Institucionální podpora UEB-Q - RVO:61389030 UT WOS 000393931100012 DOI 10.1016/j.chemosphere.2016.12.055 Anotace Non-steroidal anti-inflammatory drugs (NSAIDs) belong to most used pharmaceuticals in the human and veterinary medicine. The widespread consumption of NSAIDs has led to their ubiquitous occurrence in water environment including large river systems. In the present study, concentrations of the five most frequently used NSAIDs (ibuprofen, diclofenac, naproxen, ketoprofen and indomethacin) were determined in the watercourses of the river Elbe basin in Czech Republic. The presence of the pharmaceuticals was measured at 29 sampling sites including urban and rural areas, small creeks and main tributaries of the Elbe monthly from April to December of 2011. For the NSAIDs quantitation, the comprehensive analytical method combing pentafluorobenzyl bromide (PFBBr) derivatization with highly sensitive twodimensional gas chromatography time-of-flight mass spectrometry (GCxGC-TOFMS) was developed. Although the content of all NSAIDs varied at the particular sampling points significantly, total amount of particular compounds was relatively stable during all monitored periods with only non-significant increase in the spring and autumnal months. Ibuprofen was found to be the most abundant drug with maximum concentration of 3210 ng/L, followed by naproxen, diclofenac and ketoprofen (1423.8 ng/L, 1080 ng/L and 929.8 ng/L, respectively). Indomethacin was found only at several sampling sites (maximum concentration of 693 ng/L). Concentrations of all compounds except ibuprofen were significantly higher at sampling sites with low flow rates (creeks), followed by the biggest watercourses. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2018
Počet záznamů: 1