Počet záznamů: 1
Laccase-catalyzed dimerization of glycosylated lignols
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SYSNO ASEP 0467871 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Laccase-catalyzed dimerization of glycosylated lignols Tvůrce(i) Bassanini, I. (IT)
Gavezzotti, P. (IT)
Monti, D. (IT)
Krejzová, Jana (MBU-M) RID
Křen, Vladimír (MBU-M) RID, ORCID
Riva, S. (IT)Zdroj.dok. Journal of Molecular Catalysis B-Enzymatic. - : Elsevier - ISSN 1381-1177
Roč. 134, SI (2016), s. 295-301Poč.str. 7 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova Biocatalysis ; Biooxidation ; Laccase Vědní obor RIV CE - Biochemie CEP LD15085 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora MBU-M - RVO:61388971 UT WOS 000391074700005 EID SCOPUS 85002808065 DOI https://doi.org/10.1016/j.molcatb.2016.10.019 Anotace Phenylpropanoid glucosides (PPGs) are naturally occurring and bioactive phenolic derivatives, largely distributed in plants. In this work different PPGs have been chemically or enzymatically synthesized from the lignols coniferyl and p-coumaryl alcohols as substrates for a laccase-catalyzed oxidative coupling. The biooxidation of these PPGs has been investigated here and novel dihydrobenzofuran-based structurally modified analogues have been isolated and characterized. Specifically, the presence of a carbohydrate moiety increased the water solubility of these compounds and reduced the number of dimeric products, as pinoresinol-like structures could not be formed. Looking for a possible sugar-promoted stereochemical enrichment of the obtained diastereomeric mixtures of dimers, different carbohydrate moieties (D-glucose, L-glucose and the disaccharide rutinose) were considered and the respective d.e. values of the dimeric products were measured by 1H NMR and HPLC. However, it was found that the sugar substituent had a minor effect on the stereochemical outcome of the radical coupling reactions, the best measured result being a d.e. value of 21 Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2017
Počet záznamů: 1