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Nano-structured and functionalized surfaces for cytocompatibility improvement and bactericidal action
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SYSNO ASEP 0449225 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Nano-structured and functionalized surfaces for cytocompatibility improvement and bactericidal action Tvůrce(i) Slepička, P. (CZ)
Kasálková-Slepičková, N. (CZ)
Siegel, J. (CZ)
Kolská, Z. (CZ)
Bačáková, Lucie (FGU-C) RID, ORCID
Švorčík, V. (CZ)Zdroj.dok. Biotechnology Advances. - : Elsevier - ISSN 0734-9750
Roč. 33, 6 Part 2 (2015), s. 1120-1129Poč.str. 10 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova polymers ; surface modification ; cell-material interaction ; tissue engineering Vědní obor RIV JJ - Ostatní materiály CEP GBP108/12/G108 GA ČR - Grantová agentura ČR Institucionální podpora FGU-C - RVO:67985823 UT WOS 000362380100009 EID SCOPUS 84942568569 DOI https://doi.org/10.1016/j.biotechadv.2015.01.001 Anotace Not only surface chemistry has an effect on material biological response, surface structures of different morphology can be constructed to guide a desirable biological outcome. Nano-patterned material surfaces have been tested with the aim of how surface geometry and physical properties on a micro- and nano-scale can effect cellular response and influence cell adhesion and proliferation. Biological functionality of solid state substrates was significantly improved by the irradiation of material with plasma discharge or laser treatment. Commonly used “artificial” polymers were treated with the aim of biocompatibility improvement. Surface physico-chemical properties of treated surfaces were determined. The enhancement of adhesion and proliferation of cells on modified substrates was investigated in vitro. Bacterial action of noble metal nano-particles (e.g. Au, Ag) on polymers was characterized. The influence of metal nano-particle grafting by using metal nano-particle suspension prepared by “green” methods was determined. Micro. And nano-patterned surfaces can be constructed as tissue scaffolds with specific functions regarding cell adhesion and proliferation or potential biosensor applications Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2016
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