Počet záznamů: 1
Migration-selection balance at multiple loci and selection on dominance and recombination
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SYSNO ASEP 0427232 Druh ASEP J - Článek v odborném periodiku Zařazení RIV Záznam nebyl označen do RIV Poddruh J Článek ve WOS Název Migration-selection balance at multiple loci and selection on dominance and recombination Tvůrce(i) Yanchukov, Alexey (UBO-W) RID, ORCID, SAI
Proulx, S. R.Celkový počet autorů 2 Zdroj.dok. PLoS ONE. - : Public Library of Science - ISSN 1932-6203
Roč. 9, č. 2 (2014), e88651Poč.str. 14 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova gene-flow ; heterogeneous environment ; multilocus clines ; genomic islands ; hybrid zones ; mate choice ; evolution ; speciation ; populations ; adaptation Vědní obor RIV EB - Genetika a molekulární biologie UT WOS 000331271500052 EID SCOPUS 84895805234 DOI https://doi.org/10.1371/journal.pone.0088651 Anotace A steady influx of a single deleterious multilocus genotype will impose genetic load on the resident population and leave multiple descendants carrying various numbers of the foreign alleles. Provided that the foreign types are rare at equilibrium, and all immigrant genes are eventually eliminated by selection, the population structure can be inferred explicitly from the branching process taking place within a single immigrant lineage. Unless the migration and recombination rates were high, this novel method gives a close approximation to the simulation with all possible multilocus genotypes considered. Once the load and the foreign genotypes frequencies are known, it becomes possible to estimate selection acting on the invading modifiers of (i) dominance and (ii) recombination rate on the foreign gene block. We found that the modifiers of the (i) type are able to invade faster than the type (ii) modifier, however, this result only applies in the strong selection/low migration/low recombination scenario. Varying the number of genes in the immigrant genotype can have a non-monotonic effect on the migration load and the modifier's invasion rate: although blocks carrying more genes can give rise to longer lineages, they also experience stronger selection pressure. The heaviest load is therefore imposed by the genotypes carrying moderate numbers of genes. Pracoviště Ústav biologie obratlovců Kontakt Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524 Rok sběru 2015
Počet záznamů: 1