Počet záznamů: 1
Targeting mitochondria for cancer treatment
- 1.0387380 - ÚFE 2013 RIV IT eng J - Článek v odborném periodiku
Pokorný, Jiří - Cifra, Michal - Jandová, Anna - Kučera, Ondřej - Šrobár, Fedor - Vrba, J. - Vrba, J. - Kobilková, J.
Targeting mitochondria for cancer treatment.
European Journal of Oncology. Roč. 17, č. 1 (2012), s. 23-36. ISSN 1128-6598
Grant CEP: GA ČR(CZ) GAP102/11/0649; GA ČR GAP102/10/0120
Institucionální podpora: RVO:67985882
Klíčová slova: Electromagnetic fields * Cellular biophysics * Cancer
Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika
Impakt faktor: 0.750, rok: 2012
Cancer treatment through restoration of normal mitochondrial function is analyzed. Re-opening pyruve pathway to mitochondria in glycolytic phenotype cancer cells (e.g. by dichloroacetate–DCA) restores normal static electric field, ordering water, nonlinear conditions, and low damping of microtubule oscillations resulting in normal coherent electromagnetic activity, physical processes, and apoptotic pathway. DCA clinical experience would accumulate data for new treatment drugs
Trvalý link: http://hdl.handle.net/11104/0219999
Počet záznamů: 1