0383252 - ÚMCH 2013 RIV DE eng J - Článek v odborném periodiku
Rodriguez-Emmenegger, Cesar - Houska, Milan - Bologna Alles, A. - Brynda, Eduard
Surfaces resistant to fouling from biological fluids: towards bioactive surfaces for real applications.
Macromolecular Bioscience. Roč. 12, č. 10 (2012), s. 1413-1422. ISSN 1616-5187. E-ISSN 1616-5195
Grant CEP: GA ČR GAP205/12/1702; GA ČR GAP106/12/1451; GA ČR GAP503/10/0664; GA ČR GBP205/12/G118
Výzkumný záměr: CEZ:AV0Z40500505
Institucionální podpora: RVO:61389013
Klíčová slova: affinity biosensors * blood plasma * cerebrospinal fluid
Kód oboru RIV: CD - Makromolekulární chemie
Impakt faktor: 3.742, rok: 2012 ; AIS: 0.965, rok: 2012
DOI: https://doi.org/10.1002/mabi.201200171

The fouling from four human body fluids – blood plasma, cerebrospinal fluid, urine and saliva – and four animal fluids – foetal bovine and calf sera, egg and milk – relevant to human and veterinary medicine, immunology, biology and diagnostics is assessed on antifouling SAMs and on polymer brushes of oligo(ethylene glycol) methacrylate, 2-hydroxyethyl methacrylate, carboxybetaine acrylamide and N-(2-hydroxypropyl) methacrylamide synthesized via ATRP. While important deposits from the all biofluids are observed on SAMs, a superior resistance is achieved on polymer brushes. Importantly, only poly(CBAA) and poly(HPMA) are capable of resisting the fouling from the most challenging media, blood plasma and eggs.
Trvalý link: http://hdl.handle.net/11104/0007213