Počet záznamů: 1
A General Regioselective Synthesis of 2,4-Diarylpyrimidines from 2-Thiouracil through Two Orthogonal Cross-Coupling Reactions
- 1.0377787 - ÚOCHB 2013 RIV DE eng J - Článek v odborném periodiku
Čerňová, Miroslava - Pohl, Radek - Klepetářová, Blanka - Hocek, Michal
A General Regioselective Synthesis of 2,4-Diarylpyrimidines from 2-Thiouracil through Two Orthogonal Cross-Coupling Reactions.
Synlett. Roč. 23, č. 9 (2012), s. 1305-1308. ISSN 0936-5214. E-ISSN 1437-2096
Grant ostatní: GA ČR(CZ) GAP207/12/0205
Institucionální podpora: RVO:61388963
Klíčová slova: pyrimidines * uracil * cross-coupling * palladium
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 2.655, rok: 2012
A novel efficient synthesis of 2,4-diarylpyrimidines was developed based on phosphonium-mediated Suzuki coupling of 2-(methylsulfanyl)pyrimidin-4(3H)-one (at position 4) followed by the Liebeskind–Srogl cross-coupling (at position 2) under microwave irradiation.
Trvalý link: http://hdl.handle.net/11104/0209851
Počet záznamů: 1