Počet záznamů: 1
Interaction of glutamate- and adenosine-induced decrease of acetylcholine quantal release at frog neuromuscular junction
- 1.0355368 - FGÚ 2011 RIV CZ eng J - Článek v odborném periodiku
Adámek, S. - Shakirzyanova, V. - Malomouzh, A. I. - Naumenko, N. V. - Vyskočil, František
Interaction of glutamate- and adenosine-induced decrease of acetylcholine quantal release at frog neuromuscular junction.
Physiological Research. Roč. 59, č. 5 (2010), s. 803-810. ISSN 0862-8408. E-ISSN 1802-9973
Grant CEP: GA AV ČR(CZ) IAA500110905; GA ČR GA202/09/0806
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: Endplate potentials * Guanylyl cyclase
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 1.646, rok: 2010
The depression of nerve stimulation evoked number of quanta (EPC) by glutamate was removed by inhibition of the NO production in the muscle and the NO cascade is common post-receptor pathway started by both glutamate and adenosine presynaptic receptors. Spontaneously released quanta (MEPCs) are not regulated by NO cascade in the presence of glutamate and its specific effect on the evoked release points to modulation (phosphorylation) of the voltage-dependent Ca2+ channels at the release zone that are necessary for evoked quantal release during nerve stimulation
Trvalý link: http://hdl.handle.net/11104/0194153
Počet záznamů: 1