Počet záznamů: 1
The effect of uric acid on endothelial function
- 1.0340689 - BFÚ 2010 US eng A - Abstrakt
Papežíková, Ivana - Pekarová, Michaela - Klinke, A. - Baldus, S. - Lojek, Antonín - Kubala, Lukáš
The effect of uric acid on endothelial function.
Program and Abstracts. San Francisco: Elsevier, 2009. S65. ISSN 0891-5849. E-ISSN 1873-4596.
[SFRBM's 16th Annual Meeting. 18.11.2009-22.11.2009, San Francisco]
Grant CEP: GA ČR(CZ) GP204/07/P539
Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Klíčová slova: uric acid * endothelial dysfunction * cardiovascular risk
Kód oboru RIV: AQ - Bezpečnost a ochrana zdraví, člověk-stroj
We have tested the effect of uric acid on NO production and on endothelium-dependent and endothelium-independent relaxation of mouse aortic segments. It was found that uric acid dose-dependently decreases agonist-induced NO production by cultured cells. Further, uric acid impairs endothelium-dependent vasodilatation of mouse aortic segments.
Trvalý link: http://hdl.handle.net/11104/0183880
Počet záznamů: 1