Počet záznamů: 1
Mass spectrometry as a tool for characterization of N,N-dialkylaminoethane-2-thiols - precursors and degradation products of chemical warfare agents
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SYSNO ASEP 0339840 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Mass spectrometry as a tool for characterization of N,N-dialkylaminoethane-2-thiols - precursors and degradation products of chemical warfare agents Tvůrce(i) Papoušková, B. (CZ)
Bednář, P. (CZ)
Stýskala, Jakub (UEB-Q)
Hlaváč, J. (CZ)
Barták, P. (CZ)
Lemr, K. (CZ)Zdroj.dok. Journal of Mass Spectrometry. - : Wiley - ISSN 1076-5174
Roč. 44, č. 11 (2009), s. 1604-1612Poč.str. 9 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova mass spectrometry ; chemical warfare agents ; N,N-dialkylaminoethane-2-thiols Vědní obor RIV CE - Biochemie CEZ AV0Z50380511 - UEB-Q (2005-2011) UT WOS 000272150300008 DOI 10.1002/jms.1674 Anotace N,N-dialkylaminoethane-2-thiols belong to the group of precursors and degradation products of chemical warfare agents (CWAs). These compounds were analyzed by means of electrospray ionization-multiple stage mass spectrometry (ion trap) and proposed fragments were confirmed by accurate mass measurement using a QqTOF system. The fragmentation pathways of studied compounds and the products of oxidation (formation of -S-S- linkage) were described. Some minor interesting processes, such as rearrangement of SH group, were observed and proved. A new mu LC/MS method, based on ion-pairing chromatography, was developed. Trifluoroacetic acid was employed as an ion-pairing agent to increase the low retention of compounds of interest in the reverse-phase system. The technique was compared with the UPLC/MS method, allowing fast analysis of all the studied thiols as well as an explorative control of originated disulfides. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2010
Počet záznamů: 1