Počet záznamů: 1
Assessment of the potential risk of infection associated with Clostridium difficile from porcine xenografts
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SYSNO ASEP 0335551 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Assessment of the potential risk of infection associated with Clostridium difficile from porcine xenografts Tvůrce(i) Bakri, M.M. (GB)
Sutherland, A.D. (GB)
Brown, D.J. (GB)
Veselý, Pavel (UMG-J)
Crossan, C. (GB)
Scobie, L. (GB)Celkový počet autorů 6 Zdroj.dok. Xenotransplantation - ISSN 0908-665X
Roč. 16, č. 6 (2009), s. 472-476Poč.str. 5 s. Jazyk dok. eng - angličtina Země vyd. SG - Singapur Klíč. slova C. difficile ; hospital acquired infection ; xenotransplant ; zoonoses Vědní obor RIV EB - Genetika a molekulární biologie CEZ AV0Z50520514 - UMG-J (2005-2011) UT WOS 000273007400003 DOI 10.1111/j.1399-3089.2009.00538.x Anotace There are numerous concerns over the potential transfer of pathogens between species during clinical xenotransplantation. Porcine xenografts have been previously used to treat patients with severe burns. As pigs are a known source of zoonotic agents, many diseases must be excluded from pigs used for xenotransplantation. Clostridium difficile is a major cause of neonatal enteritis in pigs, with an important feature that pigs can be its asymptomatic carriers. We examined the incidence of C. difficile PCR ribotypes present in healthy donor pigs to determine if pig faeces, and in particular contamination of skin with faeces, is a potential route for the transfer of C. difficile. Animals were found to have human ribotype 017 present in the faecal matter, but no C. difficile was isolated from skin samples taken from the same animals. Also, due to the risk factors associated with C. difficile infection, the antimicrobial susceptibility of the C. difficile isolates has been determined. Pracoviště Ústav molekulární genetiky Kontakt Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Rok sběru 2010
Počet záznamů: 1