actinomycin D ; nuclear DNA helicase II ; transcription
Vědní obor RIV
EB - Genetika a molekulární biologie
CEP
IAA5039202 GA AV ČR - Akademie věd
CEZ
AV0Z5039906 - UEM-P
Anotace
Nuclear DNA helicase II (DNH II) is a member of the DEAH superfamily of helicases and functions as a premRNA- and mRNA-binding protein in human cells. Here we report for the first time that human NDH II is associated with the nucleolus of transformed and nontransformed cells as shown by immunofluorescence and by ultrastructural studies.