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Fibroblasts adhesion on ion beam modified
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SYSNO ASEP 0101872 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Ostatní články Název Fibroblasts adhesion on ion beam modified Překlad názvu Adhese fibroblastů na polyethylenu modifikovaném iontovou implatací Tvůrce(i) Švorčík, V. (CZ)
Tomsov, P. (RU)
Dvornkov, B. (RU)
Hnatowicz, Vladimír (UJF-V) RID
Ochsner, R. (DE)
Ryssel, H. (DE)Zdroj.dok. Nuclear Instruments & Methods in Physics Research Section B. - : Elsevier - ISSN 0168-583X
Roč. 215, 3/4 (2004), s. 366-372Poč.str. 7 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova modified polyethylene ; ion beam ; polarity Vědní obor RIV BG - Jaderná, atomová a mol. fyzika, urychlovače CEP GA106/03/0514 GA ČR - Grantová agentura ČR CEZ AV0Z1048901 - UJF-V Anotace Polyethylene (PE) was irradiated with 15 keV O+, P+ and Ar+ ions to the fluences from 3 x 10(12) to 1 X 10(15) cm(-2). The changes of surface structure and polarity and oxygen concentration were examined on pristine and as-irradiated PE. The in vitro adhesion of rat 3T3 fibroblasts on the modified PE was evaluated 24 h after inoculation. Degradation of PE is manifested by the creation of conjugated double bonds and oxidation of the PE main chain. It was proved that the implanted P atoms are chemically bound onto degraded polymer chain. Wettability of the polymer surface is affected by the structure and composition of the modified surface layer. In comparison with pristine PE (i) higher cell adhesion is observed on implanted PE and (ii) the cells cultivated on implanted PE are larger and their adherence is significantly more homogeneous. The enhancement of 3T3 cells adhesion is highest and smallest for PE implanted with O+ and Ar+ ions, respectively. Highest cell adhesion was observed on PE implanted to the fluence of 1 x 10(13) cm(-2) regardless of the ion specie. It was shown that the cell adhesion is related to the wettability of the PE surface and that there exists an optimal wettability with respect to the cell adhesion Pracoviště Ústav jaderné fyziky Kontakt Markéta Sommerová, sommerova@ujf.cas.cz, Tel.: 266 173 228 Rok sběru 2005
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