Počet záznamů: 1
Multifunctional Oxidized Dextran as a Matrix for Stabilization of Octahedral Molybdenum and Tungsten Iodide Clusters in Aqueous Media
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SYSNO ASEP 0573611 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Multifunctional Oxidized Dextran as a Matrix for Stabilization of Octahedral Molybdenum and Tungsten Iodide Clusters in Aqueous Media Tvůrce(i) Pronina, E. V. (RU)
Vorotnikov, Y. A. (RU)
Pozmogova, T.N. (RU)
Tsygankova, A. R. (RU)
Kirakci, Kaplan (UACH-T) SAI, RID, ORCID
Lang, Kamil (UACH-T) SAI, RID, ORCID
Shestopalov, M.A. (RU)Celkový počet autorů 7 Číslo článku 10010 Zdroj.dok. International Journal of Molecular Sciences. - : MDPI
Roč. 24, č. 12 (2023)Poč.str. 15 s. Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova cytotoxicity ; hydrolysis ; luminescence ; molybdenum ; octahedral iodide cluster ; oxidized dextran polysaccharide ; photodynamic therapy ; stability ; tungsten Obor OECD Inorganic and nuclear chemistry Vědní obor RIV – spolupráce Anorganická chemie CEP GA21-11688S GA ČR - Grantová agentura ČR Způsob publikování Open access Institucionální podpora UACH-T - RVO:61388980 UT WOS 001015277500001 EID SCOPUS 85164019146 DOI 10.3390/ijms241210010 Anotace Due to their high abundance, polymeric character, and chemical tunability, polysaccharides are perfect candidates for the stabilization of photoactive nanoscale objects, which are of great interest in modern science but can be unstable in aqueous media. In this work, we have demonstrated the relevance of oxidized dextran polysaccharide, obtained via a simple reaction with H2O2, towards the stabilization of photoactive octahedral molybdenum and tungsten iodide cluster complexes [M6I8}(DMSO)6](NO3)4 in aqueous and culture media. The cluster-containing materials were obtained by co-precipitation of the starting reagents in DMSO solution. According to the data obtained, the amount and ratio of functional carbonyl and carboxylic groups as well as the molecular weight of oxidized dextran strongly affect the extent of stabilization, i.e., high loading of aldehyde groups and high molecular weight increase the stability, while acidic groups have some negative impact on the stability. The most stable material based on the tungsten cluster complex exhibited low dark and moderate photoinduced cytotoxicity, which together with high cellular uptake makes these polymers promising for the fields of bioimaging and PDT. Pracoviště Ústav anorganické chemie Kontakt Jana Kroneislová, krone@iic.cas.cz, Tel.: 311 236 931 Rok sběru 2024 Elektronická adresa https://hdl.handle.net/11104/0344013
Počet záznamů: 1