Počet záznamů: 1
Pre-implant Heart Activity Differs in Responders and Non-responders to Vagal Nerve Stimulation Therapy in Epileptic Patients
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SYSNO ASEP 0551391 Druh ASEP C - Konferenční příspěvek (mezinárodní konf.) Zařazení RIV D - Článek ve sborníku Název Pre-implant Heart Activity Differs in Responders and Non-responders to Vagal Nerve Stimulation Therapy in Epileptic Patients Tvůrce(i) Plešinger, Filip (UPT-D) RID, ORCID, SAI
Halámek, Josef (UPT-D) RID, ORCID, SAI
Chládek, J. (CZ)
Jurák, Pavel (UPT-D) RID, ORCID, SAI
Ivora, Adam (UPT-D)
Doležalová, I. (CZ)
Koriťáková, E. (CZ)
Jurková, T. (CZ)
Chrastina, J. (CZ)
Brázdil, M. (CZ)Zdroj.dok. 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). - New York : IEEE, 2021 - ISBN 978-1-7281-1179-7 Rozsah stran s. 5816-5819 Poč.str. 4 s. Forma vydání Online - E Akce Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) /43./ Datum konání 01.11.2021 - 05.11.2021 Místo konání online Země MX - Mexiko Typ akce WRD Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova epilepsy ; Vagal Nerve Stimulation ; signal processing ; heart rate Vědní obor RIV FS - Lékařská zařízení, přístroje a vybavení Obor OECD Medical engineering CEP NV19-04-00343 GA MZd - Ministerstvo zdravotnictví Institucionální podpora UPT-D - RVO:68081731 UT WOS 000760910505098 EID SCOPUS 85122533694 DOI 10.1109/EMBC46164.2021.9629577 Anotace Vagal Nerve Stimulation (VNS) is used to treat patients with pharmacoresistant epilepsy. However, generally accepted tools to predict VNS response do not exist. Here we examined two heart activity measures - mean RR and pNN50 and their complex behavior during activation in pre-implant measurements. The ECG recordings of 73 patients (38 responders, 36 non-responders) were examined in a 30-sec floating window before (120 sec), during (2x120 sec), and after (120 sec) the hyperventilation by nose and mouth. The VNS response differentiation by pNN50 was significant (min p=0.01) in the hyperventilation by a nose with a noticeable descendant trend in nominal values. The mean RR was significant (p=0.01) in the rest after the hyperventilation by mouth but after an approximately 40-sec delay. Clinical Relevance: Our study shows that pNN50 and mean RR can be used to distinguish between VNS responders and non-responders. However, details of dynamic behavior showed how this ability varies in tested measurement segments. Pracoviště Ústav přístrojové techniky Kontakt Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Rok sběru 2022 Elektronická adresa https://ieeexplore.ieee.org/document/9629577
Počet záznamů: 1