Počet záznamů: 1
The effects of repeated delivery of angiotensin II AT1 receptor antisense on distinct vasoactive systems in Ren-2 transgenic rats: young vs. adult animals
- 1.0380424 - FGÚ 2013 RIV JP eng J - Článek v odborném periodiku
Vaněčková, Ivana - Dobešová, Zdenka - Kuneš, Jaroslav - Zicha, Josef
The effects of repeated delivery of angiotensin II AT1 receptor antisense on distinct vasoactive systems in Ren-2 transgenic rats: young vs. adult animals.
Hypertension Research. Roč. 35, č. 7 (2012), s. 761-768. ISSN 0916-9636. E-ISSN 1348-4214
Grant CEP: GA AV ČR(CZ) IAA500110902; GA ČR(CZ) GAP304/12/0259
Institucionální podpora: RVO:67985823
Klíčová slova: AT(1) receptor * BP regulation * gene therapy * oligodeoxynucleotides * vasodilator and vasoconstrictor systems
Kód oboru RIV: FA - Kardiovaskulární nemoci vč. kardiochirurgie
Impakt faktor: 2.791, rok: 2012
Repeated antisense therapy against Angiotensin II AT1 receptor had transient antihypertensive effects exclusively in young Ren-2 transgenic rats (TGR). The contribution of the renin-angiotensin system to blood pressure maintenance is highly important in homozygous TGR, whereas it is surpassed by sympathetic nervous system in heterozygous TGR
Trvalý link: http://hdl.handle.net/11104/0211139
Počet záznamů: 1