Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors

SKÁCEL, Jan, DJUKIC, Stefan, BASZCZYŇSKI, Ondřej, KALČIC, Filip, BÍLEK, Tadeáš, CHALUPSKÝ, Karel, KOZÁK, Jaroslav, DVOŘÁKOVÁ, Alexandra, TLOUŠŤOVÁ, Eva, KRÁĽOVÁ, Zuzana, ŠMÍDKOVÁ, Markéta, VOLDŘICH, Jan, RUMLOVÁ, M., PACHL, Petr, BRYNDA, Jiří, VUČKOVÁ, Tereza, FÁBRY, Milan, SNÁŠEL, Jan, PICHOVÁ, Iva, ŘEZÁČOVÁ, Pavlína, MERTLÍKOVÁ-KAISEROVÁ, Helena, JANEBA, Zlatko. Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors. Journal of Medicinal Chemistry. 2023, 66(10), 6652-6681. ISSN 0022-2623. E-ISSN 1520-4804. Dostupné z: doi: 10.1021/acs.jmedchem.2c02097.