Počet záznamů: 1
Polarized Sonic Hedgehog Protein Localization and a Shift in the Expression of Region-Specific Molecules Is Associated With the Secondary Palate Development in the Veiled Chameleon
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SYSNO ASEP 0532002 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Polarized Sonic Hedgehog Protein Localization and a Shift in the Expression of Region-Specific Molecules Is Associated With the Secondary Palate Development in the Veiled Chameleon Tvůrce(i) Hampl, Marek (UZFG-Y) ORCID
Dumková, J. (CZ)
Kavková, M. (CZ)
Dosedělová, Hana (UZFG-Y)
Bryjová, Anna (UBO-W) SAI, ORCID
Zahradníček, Oldřich (UEM-P) RID
Pyszko, M. (CZ)
Macholán, Miloš (UZFG-Y) RID, ORCID
Zikmund, T. (CZ)
Kaiser, J. (CZ)
Buchtová, Marcela (UZFG-Y) RID, ORCIDČíslo článku 572 Zdroj.dok. Frontiers in Cell and Developmental Biology. - : Frontiers Research Foundation - ISSN 2296-634X
Roč. 8, JUL 28 (2020)Poč.str. 29 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova secondary palate ; SHH ; primary cilia ; skeletogenesis ; chameleon ; reptile Vědní obor RIV EB - Genetika a molekulární biologie Obor OECD Developmental biology Vědní obor RIV – spolupráce Ústav biologie obratlovců - Genetika a molekulární biologie CEP GA18-04859S GA ČR - Grantová agentura ČR EF15_003/0000460 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Způsob publikování Open access Institucionální podpora UZFG-Y - RVO:67985904 ; UEM-P - RVO:68378041 ; UBO-W - RVO:68081766 UT WOS 000561204000001 EID SCOPUS 85089346331 DOI 10.3389/fcell.2020.00572 Anotace Secondary palate development is characterized by the formation of two palatal shelves on the maxillary prominences, which fuse in the midline in mammalian embryos. However, in reptilian species, such as turtles, crocodilians, and lizards, the palatal shelves of the secondary palate develop to a variable extent and morphology. While in most Squamates, the palate is widely open, crocodilians develop a fully closed secondary palate. Here, we analyzed developmental processes that underlie secondary palate formation in chameleons, where large palatal shelves extend horizontally toward the midline. The growth of the palatal shelves continued during post-hatching stages and closure of the secondary palate can be observed in several adult animals. The massive proliferation of a multilayered oral epithelium and mesenchymal cells in the dorsal part of the palatal shelves underlined the initiation of their horizontal outgrowth, and was decreased later in development. The polarized cellular localization of primary cilia and Sonic hedgehog protein was associated with horizontal growth of the palatal shelves. Moreover, the development of large palatal shelves, supported by the pterygoid and palatine bones, was coupled with the shift inMeox2,Msx1, andPax9gene expression along the rostro-caudal axis. In conclusion, our results revealed distinctive developmental processes that contribute to the expansion and closure of the secondary palate in chameleons and highlighted divergences in palate formation across amniote species. Pracoviště Ústav živočišné fyziologie a genetiky Kontakt Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Rok sběru 2021 Elektronická adresa https://www.frontiersin.org/articles/10.3389/fcell.2020.00572/full
Počet záznamů: 1