Počet záznamů: 1
Modification of Biomacromolecules with Six-valent Osmium Complexes and Electrochemical Analysis of the Modified Products
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SYSNO ASEP 0506501 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Modification of Biomacromolecules with Six-valent Osmium Complexes and Electrochemical Analysis of the Modified Products Tvůrce(i) Trefulka, Mojmír (BFU-R) RID, ORCID Celkový počet autorů 1 Zdroj.dok. Chemické listy. - : Česká společnost chemická - ISSN 0009-2770
Roč. 112, č. 9 (2018), s. 590-597Poč.str. 8 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. CZ - Česká republika Klíč. slova adsorptive stripping voltammetry ; nucleic-acids ; os(vi)-modified polysaccharides ; mercury-electrodes Vědní obor RIV CB - Analytická chemie, separace Obor OECD Analytical chemistry Způsob publikování Omezený přístup Institucionální podpora BFU-R - RVO:68081707 UT WOS 000447409400004 Anotace This review is focused on the reaction of 1,2-diols with ligand complexes of six-valent osmium [Os(VI)L] (where L is a nitrogenous ligand) and possibilities of electrochemical analysis of yielded products. A number of biologically important molecules, such as mono-, oligo- and polysaccharides, RNA and glycoproteins, belong to compounds containing 1,2-diol in their structure. These compounds react with Os(VI) L yielding relatively stable ligand osmate esters which are electrochemically active and suitable to the electrochemical analysis. The ligand osmate esters give redox peaks at the mercury and carbon electrodes. The redox peaks are due to the electrochemical reduction or oxidation of osmium atoms. The osmate esters with some ligands give catalytic peaks at the mercury electrodes. The catalytic peak is due to the catalytic hydrogen evolution and is very sensitive. With the catalytic peak it is possible to measure picomolar concentrations in some cases. We have used reactions of Os(VI) L for the analysis of glycans and glycoproteins in relation to their great importance in biomedicine. Pracoviště Biofyzikální ústav Kontakt Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Rok sběru 2020 Elektronická adresa https://www.researchgate.net/publication/329251891_Modification_of_bio_macromolecules_with_six-valent_osmium_complexes_and_electrochemical_analysis_of_the_modified_products
Počet záznamů: 1