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MoS2 Nanoparticles as Electrocatalytic Labels in Magneto-Immunoassays
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SYSNO ASEP 0490750 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název MoS2 Nanoparticles as Electrocatalytic Labels in Magneto-Immunoassays Tvůrce(i) Bouša, D. (CZ)
Mayorga-Martinez, C. C. (CZ)
Mazánek, V. (CZ)
Sofer, Z. (CZ)
Boušová, Kristýna (UOCHB-X) ORCID
Pumera, M. (CZ)Zdroj.dok. ACS Applied Materials and Interfaces. - : American Chemical Society - ISSN 1944-8244
Roč. 10, č. 19 (2018), s. 16861-16866Poč.str. 6 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova bipolar electrochemistry ; nanoparticles ; molybdenum disulphide ; immunoassay ; hydrogen evolution reaction Vědní obor RIV CG - Elektrochemie Obor OECD Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis) Institucionální podpora UOCHB-X - RVO:61388963 UT WOS 000432753800071 EID SCOPUS 85047207579 DOI 10.1021/acsami.8b01607 Anotace Ability to detect biomolecules with a simple and cost-effective approach has been very demanding in today's medicine. The nanoparticles and two-dimensional materials have been extensively used within this field in devices with high selectivity and sensitivity. Here, we report the use of MoS2 nanoparticles (MoS2 NPs) as a signal-enhancing label in a standard immunoassay test. MoS2 NPs were prepared by a bipolar electrochemistry method. The current response during the hydrogen evolution reaction catalyzed by MoS2 was measured. This current was directly proportional to the amount of the MoS2 NPs and thus also to the concentration of desired protein. The immunoassay containing the MoS2 NPs displays extraordinary low limit of detection (1.94 pg mL(-1)), good selectivity, and reproducibility. This MoS2 NP detection system could have profound implication for analytical applications. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Rok sběru 2019
Počet záznamů: 1