Počet záznamů: 1
Effects of aging and hypertension on the participation of endothelium-derived constricting factor (EDCF) in norepinephrine-induced contraction of rat femoral artery
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SYSNO ASEP 0364301 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Effects of aging and hypertension on the participation of endothelium-derived constricting factor (EDCF) in norepinephrine-induced contraction of rat femoral artery Tvůrce(i) Líšková, Silvia (FGU-C)
Petrová, M. (SK)
Karen, Petr (FGU-C)
Kuneš, Jaroslav (FGU-C) RID, ORCID
Zicha, Josef (FGU-C) RID, ORCID, SAIZdroj.dok. European Journal of Pharmacology. - : Elsevier - ISSN 0014-2999
Roč. 667, 1-3 (2011), s. 265-270Poč.str. 6 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova EDCF ; SHR ; norepinephrine ; L-NNA ; indomethacin Vědní obor RIV FA - Kardiovaskulární nemoci vč. kardiochirurgie CEP GA305/09/0336 GA ČR - Grantová agentura ČR IAA500110902 GA AV ČR - Akademie věd CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000295056800038 DOI 10.1016/j.ejphar.2011.05.031 Anotace Endothelium-dependent contraction elicited by high concentrations of acetylcholine was described in hypertensive as well as in aged normotensive rats. The contribution of endothelium-derived constricting factor (EDCF) to norepinephrine-induced contraction is still unknown. We aimed to compare EDCF participation to norepinephrine-induced arterial contraction in spontaneously hypertensive rats (SHR) and aged normotensive Wistar-Kyoto (WKY) rats. We conclude that EDCF contribution to norepinephrine-induced contraction of conduit arteries is similarly enhanced in adult hypertensive and aged normotensive rats Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2012
Počet záznamů: 1