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Inactivation of influenza virus as representative of enveloped RNA viruses on photocatalytically active nanoparticle and nanotubular TiO2 surfaces
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SYSNO ASEP 0583888 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Inactivation of influenza virus as representative of enveloped RNA viruses on photocatalytically active nanoparticle and nanotubular TiO2 surfaces Tvůrce(i) Baudys, M. (CZ)
Sopha, H. (CZ)
Hodek, Jan (UOCHB-X) RID, ORCID
Rusek, J. (CZ)
Bartková, H. (CZ)
Ulrychová, Lucie (UOCHB-X) ORCID
Macák, J. M. (CZ)
Weber, Jan (UOCHB-X) RID, ORCID
Krýsa, J. (CZ)Číslo článku 114511 Zdroj.dok. Catalysis Today. - : Elsevier - ISSN 0920-5861
Roč. 430, March (2024)Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova TiO2 ; photocatalysis ; nanotubular layer ; porosity ; virucidal ; influenza virus CEP LTAIZ19017 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Výzkumná infrastruktura CEMNAT III - 90237 - Univerzita Pardubice / Fakulta chemicko-technologická Způsob publikování Omezený přístup Institucionální podpora UOCHB-X - RVO:61388963 UT WOS 001170622800001 EID SCOPUS 85185187756 DOI 10.1016/j.cattod.2024.114511 Anotace The recent pandemic showed us that there is a strong demand for standardized methods to evaluate the antiviral activity of different materials using enveloped RNA viruses (e.g. SARS-CoV-2, influenza virus). Virucidal activity can be achieved as a result of photoexcitation of a TiO2 photocatalyst under UV illumination. All standardized methods evaluating the virucidal activity of photocatalytic surfaces use bacteriophage Qbeta, a representative of small nonenveloped viruses. This work was thus devoted to the evaluation of the virucidal efficiency of photocatalytically active nanostructured TiO2 surfaces (nanotubular and nanoparticle) to inactivate the influenza virus with particular interest paid to the methodology of virucidal testing and the influence of the surface nanostructure (porosity). Two different TiO2 nanostructures were used in this study, namely nanoparticle and nanotubular structures. A significant decrease in the amount of viral RNA and titre was obtained after rinsing, because the virus was retained on the surface of the nanostructured TiO2 during exposure in the dark. The decrease can be understood as an additional effect of the surface porosity on the TiO2 virucidal activity after UV illumination. However, this fact was taken into account in the calculation of virucidal activity due to UV light. Both nanostructured TiO2 coatings have comparable porosity and thickness, but the photocatalytic activity (to oxidatively degrade aqueous pollutants) is higher for the nanoparticle than for the nanotubular surface. On the other hand, the virucidal activity is much higher for the nanotubular surface. This can be explained by the uniform and open structure of nanotubes resulting in a lower amount of virus being retained on the surface under dark conditions and the high surface area of the nanotubes. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Rok sběru 2025 Elektronická adresa https://doi.org/10.1016/j.cattod.2024.114511
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