Počet záznamů: 1
Antibacterial photodynamic activity of carbon quantum dots/polydimethylsiloxane nanocomposites against Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae
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SYSNO ASEP 0511867 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Antibacterial photodynamic activity of carbon quantum dots/polydimethylsiloxane nanocomposites against Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae Tvůrce(i) Marković, Z. M. (RS)
Kováčová, M. (SK)
Humpolíček, P. (CZ)
Budimir, M. D. (RS)
Vajďák, J. (CZ)
Kubát, Pavel (UFCH-W) RID, ORCID, SAI
Mičušík, M. (SK)
Švajdlenková, H. (SK)
Danko, M. (SK)
Capáková, Z. (CZ)
Lehocký, M. (CZ)
Todorović Marković, B. M. (RS)
Špitalský, Z. (SK)Zdroj.dok. Photodiagnosis and Photodynamic Therapy . - : Elsevier - ISSN 1572-1000
Roč. 26, JUN 2019 (2019), s. 342-349Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova singlet oxygen generation ; methylene-blue ; antimicrobial activity ; dots ; light ; nanoparticles ; silicone ; violet ; Hydrophobic carbon quantum dots Vědní obor RIV CF - Fyzikální chemie a teoretická chemie Obor OECD Physical chemistry CEP GA19-09721S GA ČR - Grantová agentura ČR Způsob publikování Omezený přístup Institucionální podpora UFCH-W - RVO:61388955 UT WOS 000474330400058 EID SCOPUS 85065202835 DOI 10.1016/j.pdpdt.2019.04.019 Anotace Despite great efforts, the design of antibacterial surfaces is still a challenge. In this work, results of structural, mechanical, cytotoxic and antibacterial activities of hydrophobic carbon quantum dots/polydimethylsiloxane surfaces are presented. Antibacterial action of this surface is based on the generation of reactive oxygen species which cause bacteria damage by oxidative stress. At the same time, this surface was not cytotoxic towards the NIH/3T3 cells. Swelling-encapsulation-shrink method is applied for encapsulation of hydrophobic carbon quantum dots in medical grade silicone-polydimethylsiloxane. XPS and photoluminescence spectroscopy analyses confirm that hydrophobic carbon quantum dots have been encapsulated successfully into polydimethylsiloxane polymer matrix. Based on stress-strain test the improvement of mechanical properties of these nanocomposites is established. It is shown by electron paramagnetic resonance spectroscopy and luminescence method that nanocomposite generates singlet oxygen initiated by 470 nm blue light irradiation. Antibacterial testing shows the nanocomposite in the form of foil kills Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae and is very effective after only a 15 min irradiation. Pracoviště Ústav fyzikální chemie J.Heyrovského Kontakt Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Rok sběru 2020 Elektronická adresa http://hdl.handle.net/11104/0302113
Počet záznamů: 1