Počet záznamů: 1
Gut microbiome of coexisting BaAka pygmies and Bantu reflects gradients of traditional subsistence patterns
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SYSNO ASEP 0457292 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Gut microbiome of coexisting BaAka pygmies and Bantu reflects gradients of traditional subsistence patterns Tvůrce(i) Gomez, A. (US)
Petrželková, Klára Judita (UBO-W) RID, SAI, ORCID
Burns, M. B. (US)
Yeoman, C. J. (US)
Amato, K. R. (US)
Vlčková, K. (CZ)
Modrý, D. (CZ)
Todd, A. (CF)
Robinson, C. A. J. (US)
Remis, M. J. (US)
Torralba, M. (US)
Morton, E. (US)
Umana, J. D. (US)
Carbonero, F. (US)
Gaskins, H. R. (US)
Nelson, K. (US)
Wilson, B. A. (US)
Stumpf, R. M. (US)
White, B. A. (US)
Leigh, S. R. (US)
Blekhman, R. (US)Celkový počet autorů 21 Zdroj.dok. Cell Reports. - : Cell Press - ISSN 2211-1247
Roč. 14, č. 9 (2016), s. 2142-2153Poč.str. 13 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova western lowland gorillas ; microbiome ; metabolomics ; foraging ecology ; anthropogenic interactions Vědní obor RIV EG - Zoologie CEP GA206/09/0927 GA ČR - Grantová agentura ČR Institucionální podpora UBO-W - RVO:68081766 UT WOS 000371466900012 EID SCOPUS 84960468261 DOI 10.1016/j.celrep.2016.02.013 Anotace To understand how the gut microbiome is impacted by human adaptation to varying environments, we explored gut bacterial communities in the BaAka rainforest hunter-gatherers and their agriculturalist Bantu neighbors in the Central African Republic. Although the microbiome of both groups is compositionally similar, hunter-gatherers harbor increased abundance of Prevotellaceae, Treponema, and Clostridiaceae, while the Bantu gut microbiome is dominated by Firmicutes.Comparisons with US Americans reveal microbiome differences between Africans and westerners but show western-like features in the Bantu, including an increased abundance of predictive carbohydrate and xenobiotic metabolic pathways. In contrast, the hunter-gatherer gut shows increased abundance of predicted virulence, amino acid, and vitamin metabolism functions, as well as dominance of lipid and amino-acid-derived metabolites, as determined through metabolomics. Our results demonstrate gradients of traditional subsistence patterns in two neighboring African groups and highlight the adaptability of the microbiome in response to host ecology. Pracoviště Ústav biologie obratlovců Kontakt Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524 Rok sběru 2017
Počet záznamů: 1