Počet záznamů: 1
Effect of various concentrations of Ti in hydrocarbon plasma polymer films on the adhesion, proliferation and differentiation of human osteoblast-like MG-63 cells
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SYSNO ASEP 0449222 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Effect of various concentrations of Ti in hydrocarbon plasma polymer films on the adhesion, proliferation and differentiation of human osteoblast-like MG-63 cells Tvůrce(i) Vandrovcová, Marta (FGU-C) RID, ORCID
Grinevich, A. (CZ)
Drábik, M. (CZ)
Kylián, O. (CZ)
Hanuš, J. (CZ)
Staňková, Ľubica (FGU-C) RID, ORCID
Lisá, Věra (FGU-C)
Choukourov, A. (CZ)
Slavínská, D. (CZ)
Biederman, H. (CZ)
Bačáková, Lucie (FGU-C) RID, ORCIDZdroj.dok. Applied Surface Science. - : Elsevier - ISSN 0169-4332
Roč. 357, part A (2015), s. 459-472Poč.str. 14 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova metal carbon composite films ; surface wettability ; nanoscale roughness ; osteoblasts ; bone implants Vědní obor RIV EI - Biotechnologie a bionika CEP GAP108/12/1168 GA ČR - Grantová agentura ČR GA14-04790S GA ČR - Grantová agentura ČR Institucionální podpora FGU-C - RVO:67985823 UT WOS 000366216900061 EID SCOPUS 84949818408 DOI 10.1016/j.apsusc.2015.08.266 Anotace The human osteoblast-like MG-63 cells cultured on pure ppCH films and on films with 20 at% of Ti showed relatively high concentrations of ICAM-1, a marker of cell immune activation. Lower concentrations of Ti (mainly 5 at%) improved cell adhesion and osteogenic differentiation, as revealed by higher concentrations of talin, vinculin and osteocalcin. Higher Ti concentrations (15 at%) supported cell growth, as indicated by the highest final cell population densities on day 7 after seeding. Thus, enrichment of ppCH films with appropriate concentrations of Ti makes these films more suitable for potential coating of bone implants Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2016
Počet záznamů: 1