Počet záznamů: 1
Effect of altered innervation and thyroid hormones on myosin heavy chain expression and fiber type transitions: a mini-review
- 1.0443170 - FGÚ 2016 RIV DE eng J - Článek v odborném periodiku
Soukup, Tomáš - Smerdu, V.
Effect of altered innervation and thyroid hormones on myosin heavy chain expression and fiber type transitions: a mini-review.
Histochemistry and Cell Biology. Roč. 143, č. 2 (2015), s. 123-130. ISSN 0948-6143. E-ISSN 1432-119X
Grant CEP: GA MŠMT(CZ) LH12058; GA MŠMT(CZ) 7AMB14SK123
Grant ostatní: EC(XE) LSH-CT-2004-511978
Institucionální podpora: RVO:67985823
Klíčová slova: muscle fiber types * muscle regeneration * muscle transplantation * MyHC isoforms * thyroid hormone status * innervation
Kód oboru RIV: EA - Morfologické obory a cytologie
Impakt faktor: 2.780, rok: 2015
We described data regarding the effect of extrinsic factors, i.e. innervation and thyroid hormones (TH) on myosin heavy chain (MyHC) genes and on isoforms expression and consequently on muscle fiber type transitions. It has been well known, that reduced neuromuscular activity, hyperthyroidism or mechanical unloading stimulate slow to fast fiber type transitions, while increased neuromuscular activity, hypothyroidism and higher mechanical loading result in fast to slow fiber type transitions. As there is a plethora of results on these topics, we focused on data relevant to our experimental model of slow to fast muscle transformation following heterochronous intramuscular isotransplantation in rats with altered TH status
Trvalý link: http://hdl.handle.net/11104/0245913
Počet záznamů: 1