Počet záznamů: 1
The healing of alkali-injured cornea is stimulated by a novel matrix regenerating agent (RGTA, CACICOL20) – a biopolymer mimicking heparan sulfates reducing proteolytic, oxidative and nitrosative damage
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SYSNO ASEP 0398231 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název The healing of alkali-injured cornea is stimulated by a novel matrix regenerating agent (RGTA, CACICOL20) – a biopolymer mimicking heparan sulfates reducing proteolytic, oxidative and nitrosative damage Tvůrce(i) Čejková, Jitka (UEM-P) RID
Olmiere, C. (FR)
Čejka, Čestmír (UEM-P) RID
Trošan, Peter (UEM-P)
Holáň, Vladimír (UEM-P) RIDCelkový počet autorů 5 Zdroj.dok. Histology and Histopathology. - : Universidad de Murcia - ISSN 0213-3911
Roč. 29, č. 4 (2014), s. 457-478Poč.str. 22 s. Jazyk dok. eng - angličtina Země vyd. ES - Španělsko Klíč. slova RGTA ; alkali injury ; corneal healing Vědní obor RIV FF - ORL, oftalmologie, stomatologie CEP GAP304/11/0653 GA ČR - Grantová agentura ČR Institucionální podpora UEM-P - RVO:68378041 CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000333756800006 EID SCOPUS 84897046223 Anotace Heparan sulfate mimicking regeneration agent (RGTA) enabled the healing of the rabbit cornea, injured with highly concentrated alkali. When RGTA was applied by dropping on the damaged cornea early after the injury, it highly suppresed the development of corneal ulcerative processes. When the damaged cornea was topically treated with RGTA later after the injury – during the occurence of corneal ulcers, it healed majority of them. The healing of the alkali-injured cornea by RGTA took place due to the reduction of proteolytic, oxidative and nitrosative damage. key words (3): RGTA, alkali injury, corneal healing Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2015
Počet záznamů: 1