Escape of Tick-Borne Flavivirus from 2'-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness

EYER, Luděk, KONDO, H., ZOUHAROVÁ, D., HIRANO, M., VALDÉS, James J., MUTO, M., KASTL, T., KOBAYASHI, S., HAVIERNIK, J., IGARASHI, K., KARIWA, H., VACULOVICOVA, M., ČERNÝ, Jiří, KIZEK, R., KROEGER, A., LIENENKLAUS, S., DEJMEK, Milan, NENCKA, Radim, PALUS, Martin, SALÁT, J., DE CLERCQ, E., YOSHII, K., RŮŽEK, Daniel. Escape of Tick-Borne Flavivirus from 2'-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness. Journal of Virology. 2017, 91(21), e01028-17. ISSN 0022-538X. E-ISSN 1098-5514. Dostupné z: doi: 10.1128/JVI.01028-17