Počet záznamů: 1
Novel biologically active peptides from the venom of the solitary bee Macropis fulvipes (HYMENOPTERA: MELITTIDAE)
- 1.0338115 - ÚOCHB 2011 CZ eng C - Konferenční příspěvek (zahraniční konf.)
Monincová, Lenka - Slaninová, Jiřina - Voburka, Zdeněk - Hovorka, Oldřich - Fučík, Vladimír - Borovičková, Lenka - Bednárová, Lucie - Buděšínský, Miloš - Straka, J. - Čeřovský, Václav
Novel biologically active peptides from the venom of the solitary bee Macropis fulvipes (HYMENOPTERA: MELITTIDAE).
Biologically Active Peptides. 11th Conference. Praha: Institut of organic Chemistry and Biochemistry ASCR, 2009 - (Slaninová, J.), s. 77-80. Collection Symposium Series, 11. ISBN 978-80-86241-31-9.
[Biologically Active Peptides. Conference /11./. Praha (CZ), 22.04.2009-24.04.2009]
Grant CEP: GA ČR(CZ) GA203/08/0536
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: antimicrobial peptides * Macropis fulvipes * alpha-helical structures * amphipathicity
Kód oboru RIV: CC - Organická chemie
Two peptides (macropine-1 and macropin-2) were isolated, their structure determined by Edman degradation and mass spectrometry, which exhibited potent antimicrobial activity against both Gram-positive and -negative bacteria and moderate hemolytic activity against rat erythrocytes. We prepared several MAC-1 analogs to study the effect of their structure on antimicrobial and hemolytic activities.
Trvalý link: http://hdl.handle.net/11104/0181972
Počet záznamů: 1