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Sympathetic neural responses to smoking are age dependent
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SYSNO ASEP 0048826 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Sympathetic neural responses to smoking are age dependent Title Reakce sympatického nervového systému na kouření je závislá na věku Author(s) Hering, D. (PL)
Somers, V. K. (US)
Kára, T. (US)
Kucharska, W. (PL)
Jurák, Pavel (UPT-D) RID, ORCID, SAI
Bieniaszewski, L. (PL)
Narkiewicz, K. (PL)Source Title Journal of Hypertension. - : Lippincott Williams & Wilkins - ISSN 0263-6352
Roč. 24, č. 4 (2006), s. 691-695Number of pages 5 s. Language eng - English Country GB - United Kingdom Keywords sympathetic neural response ; blood pressure ; heart rate ; smoking Subject RIV FS - Medical Facilities ; Equipment R&D Projects GA102/05/0402 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z20650511 - UPT-D (2005-2011) UT WOS 000236596300014 Annotation We tested the hypothesis that the sympathetic neural responses to smoking are age dependent. Results: Cigarette smoking increased heart rate in both middle-aged subjects and young subjects. In comparison to younger subjects, middle-aged smokers showed similar smoking-related increases in systolic blood pressure (SBP) [10 +/- 3 versus 12 +/- 2 mmHg, respectively, not significant (NS)]. Smoking decreased sympathetic nerve activity by 28 +/- 12% of baseline values (P < 0.01) in young subjects. However, muscle sympathetic nerve activity did not change significantly after smoking in middle-aged subjects (5 +/- 8%, NS), despite the increased blood pressures, which would be expected to inhibit sympathetic activity. By contrast, in young subjects, the heart rate increase (22 +/- 2 bpm) was greater than that seen in middle-aged subjects (13 +/- 2 bpm, P < 0.01). Conclusions: The autonomic responses to smoking are age dependent. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2007
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